Biological Science and Health

Brain & neurons; Neuronal Disease Model
Room Room 211 (Building "Forum")
Date / Time 2015-07-23 14:00   --    15:58
Conveners / Session Chairs
  • Prof. RHEE, Jeong Seop (Group leader, Max-Planck Institute for Experimental Medicine) / email :rhee@em.mpg.de

    Profile: 1997.4 – 2000.3 Kyushu University, School of Medicine Department of Physiology, Faculty, Assistant Professor (tenure). 2000.4 – 2004.8.13 Max-Planck Institute biophysical Chemistry, Department of Membranbiophysik, Postdoctoral fellow 2004.8.14- 2005. 12 Baylor college of Medicine, Department of Human genetics and Neuroscience. Faculty, Assistant Professor. Since 2006 Independent Research Group Leader, Max-Planck Institute for Experimental Medicine, Synaptic Physiology group. Since 2010 GGNB Faculty member, Georg August University Goettingen, Goettingen Graduate School of Neurosciences and Molecular Biosciences. Since 2013 DZB (Developmental, Neural and Behavioral Biology) Faculty member, Georg August University Goettingen, Goettingen Graduate School of Biology and Psychology. Since 2013 Faculty member for Neuroscience program, Georg August University Goettingen, Goettingen Fields: Synaptic Physiology, Molecular Neurobiology, Electrophysiology, iPSC

Session Synopsis The studies for neuronal disease and diseases in other organs caused by dysfunction of neuronal regulation have been worked for long time, but it was not fully understood until now. The main reason is that the series of diseases are involved with complicate and delicate mechanisms as well as experimental subjects. The actual treatment regimen for human neurodegenerative diseases including variety of neuropsychiatric and neurological disorders has been thought the taboo issues because directly studying the living patient neurons is severely limited by the inaccessibility of the human brain. Thus, it has preferred the pharmacological treatment to examination of the underlying causes to the neuronal diseases although the drugs have several types of side effects. This neuronal disease session shows how to solve the enigma for clarifying the causes of human neuronal diseases. For example, instead of human, major limiting factors, they are making and using the various animal models according to the specific target disease due to the state-of-the-art genetic tools. In addition, based on technology developed for decades, the involvement of the morphological, molecular biological, functional and behavioral approaches have contributed to understanding and identifying the diseases. Also, this section describes in detail how the dysfunction of specific proteins or miRNA levels occurred in neurons change an activity of neuronal network and subsequently leads to neuronal disorder. Therefore, the content presented at this session will be an important cornerstone to study neuronal disease in the future.
Speakers
  • Prof. RYU, Soojin (University of Mainz & Max Planck Institute for Medical Research) [ 14:00 - 14:30 ]
    Title: Optogenetic Tuning of Behavioral Stress Response in Larval Zebrafish
  • Prof. JEONG, Seong-woo (Department of Physiology, Wonju College of Medicine, Yonsei University) [ 14:30 - 15:00 ]
    Title: Functional plasticity of the neural circuit controlling the arterial baroreflex in rat models of liver cirrhosis
  • Dr. JUNG, Sangyong (Auditory neuroscience institute and inner ear lab, U of Göttingen, Germany) [ 15:00 - 15:20 ]
    Title: Disruption of adaptor protein 2µ (AP-2µ) in sensory hair cells impairs vesicle replenishment and hearing
  • Dr. KYE, Min Jeong (Institute of Human Genetics, University of Cologne, Cologne, Germany) [ 15:20 - 15:40 ]
    Title: Synaptic miRNA expression in spinal muscular atrophy
  • Miss. JU, Anes (Max Planck institute for experimental medicine, Clinical neuroscience) [ 15:40 - 15:58 ]
    Title: Genetic mouse models of autism: From a multifaceted behavioral phenotype to molecular/cellular mechanistic insight
Other Topics (Poster Oral Presentation)
Room Cafeteria (Building "Forum")
Date / Time 2015-07-23 16:00   --    17:00
Conveners / Session Chairs
  • Dr. YEO, Sang-hoon (Lecturer, University of Birmingham) / email :s.yeo@bham.ac.uk

    Profile: 2015-Present Lecturer, School of Sport Exercise and Rehabilitation Sciences, The University of Birmingham. 2013-2015 Research Associate, Sensorimotor Learning Lab, Department Engineering, University of Cambridge. 2012 PhD Computer Science, The University of British Columbia (Vancouver, Canada). 2000 MS Department of Mechanical Engineering, Seoul National University. 1998 BS Department of Mechanical and Aerospatial Engineering, Seoul National University. *Research Interests: Muscle Mechanics, Computational Biomechanics, Sensorimotor Learning and Control.

Session Synopsis This poster oral presentation session will consist of 3-min talks by poster presenters. Topics will cover a wide range of biological and health science.
Speakers
  • Dr. KIM, Soo-hyun (University of London, United Kindgom) [ 16:00 - 16:03 ]
    Title: Role of WDR11 in hypogonadotrophic hypogonadism and Kallmann syndrome
  • Miss. LEE, Heyne (University of Oxford, United Kingdom) [ 16:03 - 16:06 ]
    Title: Interrogating the role of LRRK2 in human iPSC-derived macrophages
  • Ms. KANG, Hijee (École normale supérieure, France) [ 16:06 - 16:09 ]
    Title: Perceptual Learning and Memory of Temporal Information
  • Dr. CHAE, Heeyoung (Université Catholique de Louvain, Belgium) [ 16:09 - 16:12 ]
    Title: The control of insulin granule translocation and exocytosis in pancreatic β-cells
  • Mr. PAHK, Ki Joo (University College London, United Kingdom) [ 16:12 - 16:15 ]
    Title: Ultrasonic Histotripsy for Cell Therapy: An alternative novel method to intraportal hepatocyte transplantation for the treatment of metabolic liver diseases mediated by high-intensity focused ultrasound (HIFU)
  • Dr. KIM, Sung Hyun (Delft University of Technology, Netherlands) [ 16:15 - 16:18 ]
    Title: Building a repair machinery on the fly: How RecA uses ATP energy to make a seamless filament
  • Dr. JANG, Su Chul (University of Gothenburg, Sweden) [ 16:18 - 16:21 ]
    Title: Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors
  • Dr. RYU, Dongryeol (École Polytechnique Fédérale de Lausanne, Switzerland) [ 16:21 - 16:24 ]
    Title: SIRT7 regulates mitochondrial function via the deacetylation of GABPβ1
  • Ms. PAIK, Su-jin (Institut Curie, France) [ 16:24 - 16:27 ]
    Title: Shaping, clustering and sorting of BmrA, a multi-drug resistance membrane transporter with specific lipids
  • Mr. LEE, Jong Hoon (AgroParisTech, France) [ 16:27 - 16:30 ]
    Title: Spatial reorganization of proopiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of POMC-EGFP mice resistant or prone to obesity
  • Dr. KOO, Seong Joo (Leibniz-Institut für Molekulare Pharmakologie, Germany) [ 16:30 - 16:33 ]
    Title: Vesicular synaptobrevin 2 levels guarded by AP180 control efficient neurotransmission
  • Ms. PARK, Joohyun (Medical University of Vienna, Austria) [ 16:33 - 16:36 ]
    Title: Development of a Silk-based degradable Matrix for Abdominal Wall Soft Tissue Reconstruction
  • Dr. YEO, Sang-hoon (University of Birmingham, United Kingdom) [ 16:36 - 16:39 ]
    Title: Winding Filament Hypothesis: a New Twist on Muscle Contraction
  • Dr. KIM, Yongsoo (Netherlands Cancer Institute, Netherlands) [ 16:39 - 16:42 ]
    Title: Drug Response Prediction Using Sanger Drug Sensitivity Data
  • Ms. KWON, Soyoung (Center for Integrative Neuroscience, Germany) [ 16:42 - 16:45 ]
    Title: Top-down attention de-correlates early visual cortex
  • Mr. LEE, Juneseung (Swiss Federal Institute of Technology in Zurich, Switzerland) [ 16:45 - 16:48 ]
    Title: Control of communication network for birds
  • Mr. PARK, Saengryeol (University of Birmingham, United Kingdom) [ 16:48 - 16:51 ]
    Title: Associations between behavioural regulation and mental as well as physical health in older adults: mediating roles of physical activity and sedentary behaviour
  • Dr. YUN, Jinhyeon (University of Helsinki, Finland) [ 16:51 - 16:54 ]
    Title: Effects of Prepartum Housing Environment on the Gestation Length and Parturition Performance in Pigs
  • Mr. BYUN, Jaegyun (RWTH Aachen University, Germany) [ 16:54 - 16:57 ]
    Title: Analyzing difference of management effect by simulating tree growth in differently managed beech forest in Eifel region in Germany
Emerging technologies in biomedical sciences
Room Room 211 (Building "Forum")
Date / Time 2015-07-23 17:00   --    18:45
Conveners / Session Chairs
  • Prof. KIM, Kyeong Kyu (Professor, Sungkyunkwan University School of Medicine) / email :kyeongkyu@skku.edu

    Profile: 2008 - Present Professor, Sungkyunkwan University School of Medicine 2000-2008 Assistant & Associate Professor, Sungkyunkwan University School of Medicine 1998-2000 Assistant Professor, Gyeongsang National University 1994-1998 Postdoctoral Fellow, University of California, Berkeley 1994 PhD, 1991 MS, 1989 BS Department of Chemistry, Seoul National University, Korea *Research Interests: Structural Biology, chemical biology & biochemistry 1) Noncanonical DNA and binding proteins 2) Host- pathogen interaction 3) Proteostasis 4) Stem cell (differentiation and cancer) Synthesis and application of nanobio hybrid materials

Session Synopsis Breakthroughs in biomedical science during the 21st century can be credited to the advent of innovative methods introduced by other areas of science. Scientists in physics, chemistry and engineering have started to take interest in biomedicine; actively participating by applying the tools of their own fields. Thus it has become possible to discover a number of new phenomena which could not be observed previously with the methods in classical biology. For example, a little twist of optics, a classic subject in physics and engineering, allows us to observe the biological phenomena in single atomic or single cell levels. This has contributed to broadening our understanding of the biological system. In addition, new scientific fields such as nanomedicine and nanobiotechnology, have emerged from the subject ‘nanoscience’ that is a main research topic for engineering and chemistry. These subjects have positively influenced the application capability of biomedical sciences. Therefore, the convergence of biology with other sciences and technologies not only deepens our knowledge of living organisms but also provides new opportunities in diagnosing and treating diseases. New techniques and topics for biomedical science are constantly emerging and being introduced. Due to this ongoing trend we will be able to open more windows in our field, consequently seeing various sides of living organisms in depth. This session has been prepared to provide information about such new technologies of biomedical sciences, and will be based on discussions led by invited speakerss who are currently engaged in the new emerging fields.
Speakers
  • Dr. SHIM, Jung-uk (Department of Physics, University of Leeds) [ 17:00 - 17:25 ]
    Title: Microfluidic approach to Facilitate Novel Way to Biology
  • Prof. JOO, Chirlmin (Delft University of Technology) [ 17:25 - 17:50 ]
    Title: A Dynamic Search Process Underlies MicroRNA Targeting
  • Dr. LEE, Sung-sik (ETH Zurich Institute of Biochemistry) [ 17:50 - 18:10 ]
    Title: Single Cell Analysis of Yeast Aging Using Microfluidics
  • Dr. KIM, Jin-young (Bio Engineering Laboratory, Department of Biosystems Science and Engineering, ETH Zurich) [ 18:10 - 18:25 ]
    Title: Body on a chip
  • Dr. RYU, Hyunryul (Department of Biomedicine, University of Basel) [ 18:25 - 18:40 ]
    Title: Investigation of Real-time Single-cell MAPK Kinetics in Microfluidics
Plants, molecules to environmental Sciences
Room Room 211 (Building "Forum")
Date / Time 2015-07-24 14:00   --    15:50
Conveners / Session Chairs
  • Dr. YANG, Seong Wook / email :swyang@plen.ku.dk
  • Prof. YANG, Seong Wook (University of Copenhagen/Yonsei University) / email :swyang@PLEN.ku.dk

    Profile: Associate Professor Department of Plant and Environmental Sciences Faculty of Sciences, University of Copenhagen Department of Systems Biology College of Life Science and Biotechnology, Yonsei University

Session Synopsis The focus of this session is to discuss how plants respond to challenges in their surroundings to maintain their life. These challenges involve abiotic and biotic stresses, light quality as well as industrial pollutions. We will discuss the responses of plants from molecular levels to macroscopic aspects – gene expression, small RNA regulation, light signaling, flowering, and drought-tolerance -, achieving an integrated understanding of the links between molecular changes and the changes in the plant as a whole. This focus aims ultimately to discuss better breeding techniques for the crop plants of the future.
Speakers
  • Prof. JUNG, Il Lae (KAERI) [ 14:00 - 14:25 ]
    Title: Cesium toxicity alters physiology in Arabidopsis thaliana.
  • Dr. CHO, Seok Keun (University of Copenhagen) [ 14:25 - 14:50 ]
    Title: COP1 E3 ligase protects HYL1 to retain microRNA biogenesis.
  • Dr. BAE, Hansol (University of Copenhagen) [ 14:50 - 15:15 ]
    Title: Classification and interaction modes of 40 rice E2 ubiquitin-conjugating enzymes with 17 rice ARM-U-box E3 ubiquitin ligases.
  • Dr. HYUN, Youbong (Max Planck Institute for Plant Breeding Research, Cologne, Germany) [ 15:15 - 15:40 ]
    Title: Integration of Diverse Environmental and Endogenous Cues for Flowering at Shoot Apical Meristem through the Evolutionary Conserved Factor SPL15
Stem cell, regeneration and cancer
Room Room 211 (Building "Forum")
Date / Time 2015-07-24 17:00   --    18:45
Conveners / Session Chairs
  • Dr. KOO, Bon-kyoung (Group Leader, Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute) / email :bkk25@cam.ac.uk

    Profile: Bon-Kyoung Koo received his PhD degree in POSTECH, Korea. During this time, he studied the role of Mind bomb-1 E3 ubiquitin ligase in the Notch signalling pathway using mouse genetics approaches. He then moved to Hubrecht Institute in the Netherlands to study the biology of intestinal stem cells in Prof Hans Clevers’ lab and found that RNF43 E3 ubiquitin ligase plays a tumour suppressor role in the intestinal stem cell by modulating the Wnt signalling pathway. Currently he leads a group in Cambridge Stem Cell Institute at the University of Cambridge. His group tries to understand how adult stem cells contribute to establish normal homeostasis in adult tissues. Bon-Kyoung is part of the Marie Curie Initial Training Network "WntsApp" and was awarded the Sir Henry Dale Fellowship in 2013 to study the role of E3 ubiquitin ligases in homeostatic regulation of intestinal stem cells. This Fellowship brings together the Royal Society and the Wellcome Trust to support the future leaders of biomedical research. In 2015, he received the prestigious ERC starting grant to investigate how Troy+ stomach stem cells maintain the stomach epithelia.

Session Synopsis Stem cell, regeneration and cancer are closely related terms. Failure in stem cell-mediated regeneration leads to tissue senescence, where as an aberrant stem cell outgrowth initiates the formation of neoplasia. Here in this session, we will have four expert scientists working in the field of adult stem cell, tissue regeneration, cancer genomics and cancer signaling. Briefly, Dr. Onur Basak will show how an adult stem cell contributes the homeostatic regeneration of adult tissue. Dr. Maximina H Yun will tell us her recent study about salamander regeneration. Dr. Young Seok Ju will present an interesting mitochondrial genomic instability in human cancergenesis. Dr. Minseong Kim will explain the cross talk between the Merlin and the Wnt pathways that are known to be important signaling for tumorigenesis.
Speakers
  • Dr. BASAK, Onur (Hubrecht Institute in Utrecht, the Netherlands) [ 17:00 - 17:25 ]
    Title: Quantitative analysis of stem cell dynamics
  • Dr. YUN, Maximina (University College London, London, UK) [ 17:25 - 17:50 ]
    Title: Molecular and cellular mechanisms underlying salamander limb regeneration
  • Dr. JU, Young Seok (Cancer Genome Project, Wellcome Trust Sanger Institute, UK) [ 17:50 - 18:10 ]
    Title: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
  • Dr. KIM, Minseong (German Cancer Research Center (DKFZ), Germany) [ 18:10 - 18:30 ]
    Title: Merlin inhibits Wnt/b-catenin signaling via inhibiting the phosphorylation of LRP6